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Transgenic Mouse Facility, University Park

Produces transgenic and gene-targeted (knockout) mice for the Penn State research community.

Services

1. Transgenic mouse production

2. Gene-targeted (knockout) mouse production

2-cell stage(production of targeted mutant mice by embryonic stem cell microinjection)

3. Other services

  • Consulting: project design, construct design, screening assays, protocols, positive and negative selection schemes, any aspect of a project (no fee)
  • Special projects: inducible promoters, Cre recombinase- LoxP2
  • Special mouse strains may be considered
  • Isolation of DNA from mouse tail clips (minimum 10/procedure)
  • Isolation of DNA from embryonic stem cell clones (minimum 50/procedure)
  • Breeding of PI selected chimera or transgenic founders
  • Expansion of embryonic stem cell line(s) and arrangements for MAP testing
  • In vivo embryo rederivation (live male).
  • In vivo embryo rederivation (cryopreserved embryos).
  • Technical training (hourly rate)

Fees

Please contact us for details of fees. Fees are subject to change if mouse pricing or husbandry charges increase.

Upcoming open houses and other events
Wed May 14 at 12:00PM in 301D Life Sciences Building: Richard Samkurashvili (Ariadne Genomics Inc) Demonstration of the Pathway Studio software for Gene Expression » details…
Fri May 23 at 12:00PM in 301D Life Sciences Building: Shimadzu Prominence Nano and GC/MS Lunch 'n Learn Shimadzu and the Proteomics and MS Core Facility will sponsor a two-part seminar » details…