MM faculty and research
Faculty associated with the Molecular Medicine Intercollege Graduate Degree Program at Penn State, together with a summary of their research interests. Faculty are listed in alphabetical order of last name. To see more information about a faculty member, click on his/her name.
| Name | Email/phone | Interests include |
|---|---|---|
Antonetti, David
|
dantonetti@psu.edu 717-531-5032 (Hershey) |
Understanding the changes in retinal vessels that occur in diabetes, in particular the increased microvessel permeability that occurs early in diabetes. |
August, Avery
|
axa45@psu.edu 814-863-3539 (University Park) |
Regulation of T cell activation, differentiation and allergic asthma induction by ltk (Tec family kinases). |
Bascom, Rebecca
|
rbascom@psu.edu 717-531-6525 (Hershey) |
Inhalation toxicology, including evaluation of cardiorespiratory effects of the 9/11 terrorist attack on New York City. |
Bronson, Sarah
|
sbronson@psu.edu 717-531-5194 (Hershey) |
Targeted transgenesis and transgene expression: stem cell differentiation/osteogenesis. |
Cameron, Craig
|
cec9@psu.edu 814-863-8705 (University Park) |
Defining the molecular details of genome replication in positive-strand RNA viruses and identifying components of this process suitable for antiviral drug development. |
Cantorna, Margherita
|
mxc69@psu.edu 814-863-2819 (University Park) |
Identification and characterization of the cellular and molecular targets of vitamin D in the immune system. |
Cavener, Douglas (Doug)
|
drc9@psu.edu 814-865-4562 (University Park) |
Regulation of gene expression underlying neonatal development & organ system physiology; mouse models of human congenital diseases including juvenile diabetes, metabolic disorders, skeletal dysplasias, and central nervous system dysfunctions. |
Clawson, Gary
|
gac4@psu.edu 717-531-5632 (Hershey) |
Early changes in carcinogenesis. |
Connor, James
|
jrc3@psu.edu 717-531-6408 (Hershey) |
Regulation of expression of iron-binding proteins in the nervous system. |
Courtney, Richard
|
rjc11@psu.edu 717-531-6521 (Hershey) |
Role of tegument proteins in the envelopment of Herpes Simplex Virus. |
Eckert, Kristin
|
kae4@psu.edu 717-531-4065 (Hershey) |
The significance of spontaneous and carcinogen-induced mutations at short tandem repeat (STR) DNA loci in human cells. |
Frisque, Richard
|
rjf6@psu.edu 814-863-3523 (University Park) |
Molecular investigation of JC virus, including the role of viral proteins in altering cell cycle progression. |
Gabbay, Robert
|
rgabbay@psu.edu 717-531-3592 (Hershey) |
Translational research efforts to improve diabetes care in both the inpatient and outpatient settings. |
Gardner, Thomas
|
tgardner@psu.edu 717-531-8783 (Hershey) |
Study of basic mechanisms which may initiate diabetic retinopathy, with particular focus on regulation of tight junction proteins. |
Glick, Adam
|
abg11@psu.edu 814-865-7170 (University Park) |
Molecular mechanisms and signaling pathways that regulate progression of squamous tumors from a benign to malignant phenotype. |
Gowda, Channe
|
gowda@psu.edu 717-531-0992 (Hershey) |
Understanding the structures and interactions between Plasmodium falciparum and human glycoconjugates that lead to malaria pathogenesis. |
Hankey, Pamela (Pam)
|
phc7@psu.edu 814-863-0128 (University Park) |
Regulation of cell-mediated immunity, hematopoiesis, receptor tyrosine kinases, cellular transformation. |
Harvill, Eric
|
harvill@psu.edu 814-863-8522 (University Park) |
Molecular basis of bacterial infection pathology (including effects of bacterial virulence factors, such as toxins). |
He, Biao
|
bxh40@psu.edu 814-863-8533 (University Park) |
Understanding how paramyxoviruses (SV5) induce and inhibit apoptosis. Using SV5 as a vector for expressing foreign genes and for live vaccine development. |
Herzog, Christopher
|
crh13@psu.edu 717-531-8285 (Hershey) |
Mechanisms by which carcinogens induce genomic instability in lung cancer. |
Hu, Jianming
|
juh13@psu.edu 717-531-6523 (Hershey) |
Virus-cell interactions in Hepatitis B Virus replication and pathogenesis. |
Irby, Rosalyn
|
rirby@psu.edu 717-531-5035 (Hershey) |
Etiology of large granular lymphocyte (LGL) leukemia. Identification of the molecular basis for metastatic disease in colorectal cancer. |
Isom, Harriet
|
hci1@psu.edu 717-531-8609 (Hershey) |
Liver pathophysiology: cellular and molecular analyses of growth control, differentiation, apoptosis, cell injury, iron metabolism and Hepatitis Virus infection in hepatic cell systems. |
Jefferson, Leonard (Jim)
|
jjefferson@psu.edu 717-531-8567 (Hershey) |
Regulation of gene expression in mammalian cells by hormones and nutrients. |
Katzman, Michael
|
mkatzman@psu.edu 717-531-8881 (Hershey) |
Retroviral integration and AIDS pathogenesis. |
Keil, Ralph
|
rkeil@psu.edu 717-531-8595 (Hershey) |
Mechanism of action of volatile inhaled anesthetics. |
Kester, Mark
|
mkester@psu.edu 717-531-8964 (Hershey) |
Regulation of kinase cascades by lipid-derived second messengers. |
Konan, Kouacou
|
kvk10@psu.edu 814-863-8254 (University Park) |
Hepatitis C and related viruses: how their replication interferes with host protein and membrane trafficking. |
LaNoue, Kathryn
|
kfl1@psu.edu 717-531-8155 (Hershey) |
Neuronal glutamate synthesis and degradation. |
Lai, Zhi-Chun
|
zcl1@psu.edu 814-863-0479 (University Park) |
Growth Control and Cancer Genetics |
Lang, Charles
|
clang@psu.edu 717-531-5538 (Hershey) |
Regulation of the IGF (Insulin-like Growth Factor) system during catabolic conditions. |
Lazarus, Philip
|
plazarus@psu.edu 717-531-5734 (Hershey) |
Mechanisms involved in the induction and progression of tobacco-related cancers. |
Lengerich, Eugene
|
ejl6@psu.edu 717-531-7178 (Hershey) |
Chronic disease epidemiology; public health surveillance; Geographic Information System (GIS); cartography; community-based research; program evaluation; health disparities; Appalachian region; rural health; screening; prevention. |
Levenson, Robert
|
rlevenson@psu.edu 717-531-4545 (Hershey) |
Molecular neurobiology, cell differentiation. |
Liu, David
|
dxl39@psu.edu 717-531-4168 (Hershey) |
Regulation of neuronal cell death and neural differentiation. |
Loughran, Thomas
|
tloughran@psu.edu 717-531-4034 (Hershey) |
Large granular lymphocyte (LGL) leukemia |
Luscher, Bernhard
|
bxl25@psu.edu 814-865-5549 (University Park) |
Structure, function and regulation of GABA-A receptors and their role in anxiety disorders. |
Lynch, Christopher
|
clynch@psu.edu 717-531-5170 (Hershey) |
Adipose tissue biology, nutrient signaling and obesity. |
Mastro, Andrea
|
a36@psu.edu 814-863-0152 (University Park) |
Breast cancer and the immune system; how metastatic, osteolytic breast cancer cells affect osteoblasts. |
McAllister, Jan
|
jxm63@psu.edu 717-531-3588 (Hershey) |
Regulation of the genes encoding steroidogenic enzymes in the human ovary. |
McLaughlin, Patricia
|
pxm9@psu.edu 717-531-6414 (Hershey) |
Growth factors and receptors in brain and heart development and cancer. The pentapeptide OGF and its receptor, OGFr; understanding the OGF-OGFr axis and its mechanisms of action in both normal and disease states. |
Meyers, Craig
|
cmm10@psu.edu 717-531-6240 (Hershey) |
Differentiation-dependent replication of papillomaviruses and their role in carcinogenesis. |
Moore, Gregory
|
gmoore@psu.edu 717-531-8646 (Hershey) |
Neuroimaging biomarkers. |
Mulder, Kathleen
|
kmm15@psu.edu 717-531-6789 (Hershey) |
TGF-beta signal transduction, anti-cancer therapeutics and diagnostics, motor proteins, and intracellular trafficking. |
Norbury, Chris
|
ccn1@psu.edu 717-531-7204 (Hershey) |
The activation of retinal microglia in the progression of diabetic retinopathy. |
Omiecinski, Curtis (Curt)
|
cjo10@psu.edu 814-863-1625 (University Park) |
Regulatory mechanisms responsible for controlling the expression of biotransformation enzymes. |
Parent, Leslie
|
lparent@psu.edu 717-531-8881 (Hershey) |
Molecular mechanisms of virus replication; intracellular trafficking pathways of retroviral proteins and cellular factors that are recruited to facilitate virus propagation. |
Paulson, Robert (Bob)
|
rfp5@psu.edu 814-863-6306 (University Park) |
Genetic and biochemical analysis of cell signaling during hematopoiesis. |
Perdew, Gary
|
ghp2@psu.edu 814-865-0400 (University Park) |
Biochemistry of heat shock protein complexes; role of 90 kDa heat shock protein in stabilization of other cytosolic proteins. |
Peters, Jeffrey
|
jmp21@psu.edu 814-863-1387 (University Park) |
Roles of peroxisome proliferator-activated receptors (PPARs) in the regulation of homeostasis, toxicology, and carcinogenesis. |
Reese, Joseph (Joe)
|
jcr8@psu.edu 814-865-1976 (University Park) |
UV resistance pathways in eukaryotes. Regulation of DNA damage inducible genes by chromatin. Role of a highly conserved RNA helicase in DNA damage resistance and viral pathogenesis. |
Richie, John
|
jrichie@psu.edu 717-531-5381 (Hershey) |
Metabolic and genetic factors that affect cancer risk. Role of glutathione in protecting against oxidative damage, and its relationship with cancer development. |
Robertson, Gavin
|
gprobertson@psu.edu 717-531-8098 (Hershey) |
Genetic regulation of melanoma development. |
Ropson, Ira
|
iropson@psu.edu 717-531-4064 (Hershey) |
Folding, function and stability of beta-sheet proteins. |
| Sample, Jeffery |
jts21@psu.edu (Hershey) |
Mechanisms of Epstein-Barr virus persistence and tumorigenesis. |
Schengrund, Cara-Lynne
|
cxs8@psu.edu 717-531-8048 (Hershey) |
Biological role of gangliosides. |
Schlegel, Robert
|
ur3@psu.edu 814-865-6974 (University Park) |
Molecular mechanisms by which an asymmetric distribution of phospholipids is maintained across the plasma membrane in animal cells. |
Simpson, Ian
|
ixs10@psu.edu 717-531-4156 (Hershey) |
Transport of nutrients across the blood-brain barrier. Cytokine-mediated activation of the brain's inflammatory/wound healing mechanisms in diabetes and strokes. |
Smith, Jill
|
jsmith2@psu.edu 717-531-3694 (Hershey) |
Peptides and growth of pancreatic cancer. |
Tan, Song
|
sxt30@psu.edu 814-865-3355 (University Park) |
Structural biology of eukaryotic gene regulation. |
Teng, Michael
|
mnt2@psu.edu 814-865-4347 (University Park) |
Interaction of viral proteins with the host; viral attachment and modulation of the antiviral immune response. |
Thiboutot, Diane
|
dthiboutot@psu.edu 717-531-8307 (Hershey) |
Factors regulating human sebum production in acne. |
Vary, Thomas
|
tvary@psu.edu 717-531-5014 (Hershey) |
Protein synthesis in inflammation and sepsis and in development of alcoholic cardiomyopathy. |
Vrana, Kent
|
kvrana@psu.edu 717-531-8285 (Hershey) |
The potential of human embryonic stem cells in regenerative medicine. |
Wang, Yanming
|
yuw12@psu.edu 814-865-3775 (University Park) |
Epigenetic histone modifications in cell differentiation and cancer. |
Xiong, Na
|
nux1@psu.edu 814-863-2933 (University Park) |
Molecular mechanisms underlying development of tissue specific gamma/delta T cells and their role in infection and inflammation. |
Zagon, Ian
|
isz1@psu.edu 717-531-8650 (Hershey) |
Peptides and receptors in development, cancer, cell renewal, wound healing, angiogenesis, cornea, neurodegeneration, diabetes and Crohn's Disease. |
Zhu, Jiyue
|
joz1@psu.edu 717-531-3597 (Hershey) |
Molecular mechanisms of cellular senescence and immortalization, and their roles in tumorigenesis. |