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Chemical Biology faculty and research

Faculty involved in the Chemical Biology option of the Integrative Biosciences graduate program, and a summary of their research interests. To see more about a faculty member, click on their name in the list below.
Name Email/phone Interests include
Amin, Shantu
  • Professor of Pharmacology
sga3@psu.edu
717-531-8285
   (Hershey)

Design and synthesis of agents to study mechanisms of cancer etiology and develop anti-cancer agents.

Bevilacqua, Philip
  • Professor of Chemistry
pcb@chem.psu.edu
814-863-3812
   (University Park)

Roles of RNA-binding proteins in plant physiology. Plant ribonomics. Identification and characterization of functional RNAs in plants.

Bewley, Maria
  • Associate Professor of Biochemistry and Molecular Biology
mcb21@psu.edu
717-531-4321
   (Hershey)

Investigation of protein function using structural techniques such as x-ray crystallography.

Bond, Judith
  • Professor and Chair Biochemistry and Molecular Biology
jbond@psu.edu
717-531-8586
   (Hershey)

Structure, function, and regulation of proteolytic enzymes.

Chen, Gong
  • Assistant Professor of Chemistry
guc11@psu.edu
   (University Park)

To apply synthetic chemistry to create novel carbohydrate and peptide-based molecules and explore their biological and therapeutic functions.

Connor, James
  • Distinguished Professor and Vice-Chair Department of Neurosurgery
jrc3@psu.edu
717-531-6408
   (Hershey)

Creation of methods to regulate expression of iron-binding proteins in the nervous system.

El-Bayoumy, Karam
  • Professor of Biochemistry and Molecular Biology
  • Associate Director of Basic Research, Penn State Cancer Institute
kee2@psu.edu
717-531-1005
   (Hershey)

Understanding the mechanisms of tobacco carcinogenesis and developing appropriate strategies for cancer chemoprevention.

Flanagan, John
  • Professor of Biochemistry and Molecular Biology
jflanagan@psu.edu
717-531-4189
   (Hershey)

Investigation of protein function, using a variety of biochemical, genetic and structural techniques including x-ray crystallography.

Gowda, Channe
  • Professor of Biochemistry and Molecular Biology
gowda@psu.edu
717-531-0992
   (Hershey)

Understanding the structures and interactions between Plasmodium falciparum and human glycoconjugates that lead to malaria pathogenesis.

Hammes-Schiffer, Sharon
  • Eberly Professor of Biotechnology and Professor of Chemistry
soh3@psu.edu
814-865-6442
   (University Park)

Theoretical and computational investigation of chemically and biologically important processes; proton, hydride, and proton-coupled electron transfer reactions; mixed quantum/classical molecular dynamics simulations; development of theoretical and computational methods; applications to reactions in solution and proteins.

Irby, Rosalyn
  • Assistant Professor of Medicine
rirby@psu.edu
717-531-5035
   (Hershey)

Etiology of large granular lymphocyte (LGL) leukemia. Identification of the molecular basis for metastatic disease in colorectal cancer.

Jefferson, Leonard (Jim)
  • Evan Pugh Professor and Chair of Cellular and Molecular Physiology
jjefferson@psu.edu
717-531-8567
   (Hershey)

Structure, function and regulation of mRNA translation initiation factors.

LaNoue, Kathryn
  • Professor of Cellular and Molecular Physiology
kfl1@psu.edu
717-531-8155
   (Hershey)

Endocrinology and transmembrane signalling. Diabetes and insulin resistance.

Mulder, Kathleen
  • Professor of Pharmacology
kmm15@psu.edu
717-531-6789
   (Hershey)

TGF-beta signal transduction, anti-cancer therapeutics and diagnostics, motor proteins, and intracellular trafficking.

Pegg, Anthony
  • Evan Pugh Professor of Cellular and Molecular Physiology, and Pharmacology
apegg@psu.edu
717-531-8152
   (Hershey)

Investigation of polyamine metabolism and DNA repair using protein engineering and x-ray crystallography.

Prokopczyk, Bogdan
  • Associate Professor of Pharmacology
bup10@psu.edu
717-531-5922
   (Hershey)

The etiology of carcinogen- and virus-induced cancers.

Robertson, Gavin
  • Assistant Professor of Pharmacology, Pathology, and Dermatology
  • Co-Chair Intercollege Graduate Degree Program in Genetics
gprobertson@psu.edu
717-531-8098
   (Hershey)

Genetic regulation of melanoma development.

Ropson, Ira
  • Associate Professor of Biochemistry and Molecular Biology
iropson@psu.edu
717-531-4064
   (Hershey)

Investigating the folding, stability and function of proteins using NMR spectroscopy.

Schengrund, Cara-Lynne
  • Professor of Biochemistry and Molecular Biology
cxs8@psu.edu
717-531-8048
   (Hershey)

Biological role of gangliosides.

Spratt, Thomas (Tom)
  • Associate Professor of Biochemistry and Molecular Biology
  • Chair, Chemical Biology option of Integrative Biosciences Graduate Program
tes13@psu.edu
717-531-4623
   (Hershey)

Design and synthesis of unnatural substrates to examine the mechanisms of DNA repair and mutagenesis.