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Center for Molecular Investigation of Neurological Disorders

Center for Molecular Investigation of Neurological Disorders

Facilitating research collaborations on neurological and neuropsychiatric disorders such as Alzheimer's, autism, epilepsy, depression, and schizophrenia

The Center for Molecular Investigation of Neurological Disorders (CMIND) facilitates research collaborations among its researchers and university wide.

Research laboratories include state of the art instrumentation for electrophysiology, imaging, molecular and cell biology, and behavioral analysis of mice.

Mission

The Center's mission is to use the latest and most appropriate tools to advance the understanding of molecular, cellular and system wide function of the nervous system, with special emphasis on mechanisms that regulate neural excitability, synaptic transmission and intracellular mechanisms of signal transduction that are relevant for understanding of neurological and neuropsychiatric disorders such as Alzheimer's, autism, epilepsy, depression, and schizophrenia.

Recent publications
Researchers identify gene required for nerve regeneration A team led by Melissa Rolls has found that a mutation in a single gene can completely shut down the process by which axons, nerve-cell components responsible for sending signals to other cells, regenerate after being damaged.
Protein required for flexible behavior is identified Researchers have identified in mice a protein that is necessary for maintaining behavioral flexibility, the ability to adapt to changing circumstances; their findings may offer new insights for addressing such human afflictions as autism and schizophrenia, in which this ability is significantly impaired.
New model synapse could shed light on disorders such as epilepsy and anxiety A team of scientists led by Huck Institutes faculty member Gong Chen has developed a new way to study the role of a critical neurotransmitter in disorders such as epilepsy, anxiety, insomnia, depression, schizophrenia, and alcohol addiction.
News
The new Molecular, Cellular and Integrative Biosciences (MCIBS) graduate program merger aims to increase integration and flexibility for life sciences students. Announcing MCIBS – a new life sciences graduate program - Full article
A new drug target to fight Alzheimer's disease has been discovered by a research team led by Gong Chen, a Professor of Biology and the Verne M. Willaman Chair in Life Sciences at Penn State University. Rescue of Alzheimer's memory deficit achieved by reducing 'excessive inhibition' - Full article
Neurobiologist Tim Jegla and his Lab find in a living, ancient sea anemone species the same gene family and ion channel that regulate the slow wave contractions of the human heart. Human heart beats using nearly billion-year-old molecular mechanism - Full article