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Ronald Duman
(Yale School of Medicine)
Stress and Depression: A Case of Neuronal Life or Death
Wed Nov 18 at 04:00PM in 108 Wartik Laboratory, CG623 Hershey
More information about Ronald Duman…
Dr. Duman’s work has focused on the molecular and cellular actions of stress, depression, and antidepressant treatments, providing the basis for a neurotrophic hypothesis of depression. This hypothesis is based on work demonstrating that stress and depression decrease neurotrophic factor expression in the brain, contributing to atrophy and loss of neurons. In contrast, chronic antidepressant treatment increases neurotrophic factor levels and increases the proliferation of new neurons in the adult brain, thereby blocking or reversing the effects of stress and depression. These findings represent groundbreaking advances in our understanding of stress and depression and provide a framework for developing novel therapeutic agents.
Questions? Want to meet with the speaker?
Contact Bernhard Luscher, bxl25@psu.edu or phone 865-5549
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