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Huck students win poster contest
Li-Lun Ho and Mankit Law pose with their winning posters.
Two Huck Institutes graduate students beat out over 300 other graduate students, including 49 in the Health and Life Sciences category, to be this years Graduate Exhibition research poster winners!
About the Graduate Exhibition
As a celebration of the best of Penn State, the Graduate Exhibition is a showcase for graduate activities. The Exhibition attracts large numbers of visitors to Penn State, who bring with them wide-ranging backgrounds and experiences. Students are encouraged to recognize the value of making their work accessible and useful to all who attend. Helping these visitors to understand the excitement the students feel for their work is an important component of the Graduate Exhibition.
Activation of Mob as tumor suppressor by membrane association in growth inhibition
Li-Lun Ho
Organ sizes are decided by cell sizes and cell numbers. In the regulation of cell numbers, cell proliferation and cell death need to be coupled and coordinated to maintain organ sizes. In the past decade, Hippo signaling pathway has been shown to restrict cell proliferation and promote cell death. Previous studies have demonstrated that a tumor suppressor protein, Mats, functions as an activating cofactor of Warts (Wts)/large tumor suppressor (Lats) protein in this pathway. Read more...
Identification of drebrin as a potential pharmacological target for immunosuppression
Mankit Law
In cells of the immune system, SOCE is essential for activation of Nuclear Factor of Activated T-cells (NFAT) and, therefore, for subsequent expression of cytokines, chemokines, and other target genes that are responsible for productive defense. Despite their importance, many of the elements of the pathway leading to SOCE remain elusive. A tool which may potentially help in the identification of these elements is a novel class of immunosuppressants, represented by 3,5-Bis(trifluoromethyl)-pyrazole (BTP) compounds. Read more...
The posters
Li-Lun Ho's winning poster entitled "Activation of Mob as tumor suppressor by membrane association in growth inhibition". Click the poster for a larger image.
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Mankit Law's winning poster entitled "Identification of drebrin as a potential pharmacological target for immunosuppression". Click the poster for a larger image.
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